Every lousy theatre has has hits (Rent) over the years and every great theatre has had bombs (Breakfast at Tiffany's).
Historically bad luck/not-sought-after houses:
Ambassador - exception Noise/Funk and transfers
Nederlander - exceptions Rent and Lena Horne
Cort - exception Magic Show
Longacre - exceptions Ain't Misbehavin' which moved to 45th Street after 8 months and The Belle of Amherst
Belasco - except those limited runs from London
No one hopes to go to the Lunt-Fontanne. They take it only if its the only house left.
No one really seeks out the Minskoff either.
"If my life weren't funny, it would just be true. And that would be unacceptable."
--Carrie Fisher