Annette Bening turned down both Marian(Robin Hood) and Catwoman(Batman Returns) because she was pregnant.
Molly Ringwald turned down Ghost(which went to Demi Moore) and Pretty Woman(which of course helped out Julia Roberts' career).
Nicole Kidman dropped out Panic Room because she was still recovering from Moulin Rouge.
Mary Martin turned down My Fair Lady.
Cary Grant was offerred Henry Higgins in the My Fair Lady movie, but said only Rex Harrison can play the role.
Oh, and I had heard that Debra Winger had agreed to do A League of Their Own, until Madonna was cast, then dropped out because this was when Madonna was still racy.
Bette Midler turned down Sister Act. Mel Gibson - The Gladiator Holly Hunter - As Good As it Gets Nancy Reagan & Esther Williams turned down Albert Brooks' "Mother" Tom Hanks - Jerry Maguire & American Beauty Debra Winger - The Piano Michelle Pfeiffer - The Silence of the Lambs Dustin Hoffman - Dead Poet's Society Robert DeNiro - Do the Right Thing Cher, Goldie Hawn & Shelly Long - Working Girl Tina Turner - (As Shug Avery) The Color Purple Jill Clayburgh, Jane Fonda & Faye Dunaway - Norma Rae
"Do you know what pledge time is, Andrew"? said the PBS Executive.
"Yes", Lloyd Webber replied. "My 50th birthday special must be one program that gets done a lot."
"No", mused the man from PBS heedlessy. "Not so much. Our Stephen Sondheim Carnegie Hall concert. That's a big one."
Spoons, forks and knives seemed suddenly to suspend their motion in horror, all around the table.