As far as I can remember, the only Tony-nominated lead in recent times who has stayed with a show longer is Gavin Lee in Mary Poppins, who has done either the Broadway or tour version for almost 6 years now.
A few featured Tony-nominated leads have stuck with their show recently, including Carole Shelley in Billy Elliot (and Greg Jbara for the most part).
"What was the name of that cheese that I like?"
"you can't run away forever...but there's nothing wrong with getting a good head start"
"well I hope and I pray, that maybe someday, you'll walk in the room with my heart"