Wicked is worth *anything*, but that said, I wouldn't have wanted my first time seeing it to be partial view. You don't miss much, but you DO miss some things completely - I was on the end of the front row and the whole birth scene was masked by ensemble. Now this was my 4th time seeing it so I wasn't bothered, but the poor people behind me were craning their necks trying to figure out what was going on...
Of the main action though, you really don't miss much, if anything. A lot of entrances if they're on the side you're on, but you won't miss anything vital. And it's really fun if you're nice and close