Your mileage may vary as to whether you think it's misogynstic, but the entire time I was in the theatre I felt I was watching a show who's attitude towards women (or sexuality, for that matter) was a generation or two behind the times. I will of course defer to other, more studied opinions (especially those of women, which alas I am not) but I felt massively uncomfortable at the source and direction of many of the jokes in the show. Others will naturally disagree as clearly many have enjoyed the show, so that's a term I leave as 'my two cents' and a characteristic description of how I felt leaving the theatre.
As for insulting, I think it's pretty clear to me that the structure of the show, **SPOILER** in which each major event happens in both timelines regardless of her choice, inherently devalues the choice itself in terms of stakes. One is left, realizing that no matter what she chose the outcomes would be same, the order of how specific events played out is all that changed, to reckon with the fact that the choice upon which hinged the plot of the thought exercise the show is built around is essentially pointless. The ending of the show undoes the reason for it's beginning. In the end, one is left with a story, cleaved in two, neither of which is interesting enough to carry a musical in it's own right, and which add up to far less than the sum of their parts. In that sense, it is a waste of time, and insults the audience in doing so. Furthermore, as far as what-if? narratives go, it contributes almost nothing to the form that many others haven't already gone over many times. It isn't saying anything new, if you can find anything it's saying at all, and whatever it is saying it's doing it rather poorly.
Words don't deserve that kind of malarkey. They're innocent, neutral, precise, standing for this, describing that, meaning the other, so if you look after them you can build bridges across incomprehension and chaos. But when they get their corners knocked off, they're no good anymore…I don't think writers are sacred, but words are. They deserve respect. If you get the right ones in the right order, you can nudge the world a little.