Haven't seen "Vera Drake," but I have loved Imelda for years! I was so excited to see her nominated, and sorry that this probably won't be her year. (I still think she and Hugh Laurie should have been Molly & Arthur Weasley in the Harry Potter movies.)
Last minute predictions (these are all my objective guesses, not necessarily what I'm rooting for):
Picture: Million Dollar Baby
Director: Clint Eastwood
Actor: Jamie Foxx
Actress: Hillary Swank
Supporting Actor: ...Morgan Freeman, although I'm not convinced of this; won't be shocked if it's Church or Owen. (If it is Freeman, I think that bodes well for M$B in the big categories.)
Supporting Actress: Virginia Madsen
Animated Feature: The Incredibles (the one thing I really care about this year...)
Screenplays: Sideways for sure, probably Eternal Sunshine (these seem like categories where they often honor the critical favorites that miss out on the big awards)
Total guess, and I haven't seen it, but I have a weird feeling "Aviator" may be one of these nominated-for-everything, wins-little-or-nothing cases.
I am probably completely wrong...
And, while I certainly don't begrudge LoTR:RotK their sweep, "Kiss at the End of the Rainbow" absolutely should have won song last year!
"In my own little corner..."