First off, I really like this show a lot and have seen it 2 times. Laurie Metcalfe is absolutely fantastic in it!
The first time, there was a lot of laughter, even at the points that weren't necessarily mean too be funny. Of course pope will laugh at a few of the one-lines and whatnot.
The second time I saw the show, the laughter was a lot lesser than the first, and more gasping and definitely was seemingly more suspenseful in the audience.