Studio 54 really is a bit too big for this play, but boy oh boy do the text and these actors FILL that space.
I just did the TodayTix rush and was indeed in the rear mezz. I was row 2 or 3 on the aisle and it was a wonderful, clear view. I was a little worried about distance with this being such an intimate play, but I could still see faces just fine. I agree with the above, you will get so sucked in it won't matter. That being said, I definitely wouldn't have wanted to be any further back. So, if you don't want to risk a "bad" seat then definitely plan accordingly! If not, the rush will be great!