I love the movie with my whole heart and I think it would make a wonderful musical.
My father (AIDS)
My sister (AIDS)
My uncle and my cousin and her best friend (AIDS, AIDS, AIDS)
The gays and the straights
And the white and the spades
I can see why you think that, but the problem is the action that takes place while the main character is a mouse would be tough to pull off since the small size in relation to the world around him is crucial.