Definitely Chita Rivera who has successfully played roles throughout her career without being ethnicized. She started as Anita and went on to play Rose in BYE BYE BIRDIE, but after that, she has played Anna in THE RINK, Velma Kelly, Reno Sweeney, the Queen in MERLIN, she was one of the stars in JERRY'S GIRL, she played LaFleur, the main role in THE VISIT, and I'm sure she has played a few more non-Latina roles in stock. She truly defied all minority barriers.
Audra McDonald is more modern, but I agree she has been able to play parts in which her race is not seen as relevant.
Same goes for Raul Esparza whom I'm sure people think of as "white." I can't think of any other Latino actors who are allowed to be in a Mamet play, a Pinter play, and a Sondheim musical without people thinking of "color-blind casting." Interestingly enough though, no one thinks of him when it comes to casting Latino male roles.
"Some people can thrive and bloom living life in a living room, that's perfect for some people of one hundred and five. But I at least gotta try, when I think of all the sights that I gotta see, all the places I gotta play, all the things that I gotta be at"