Taboo's problem was in a few places. First of all, people were afraid of it. For example, my father drove me into the city for a doctor's appointment, and we stopped at the box office so I could pick up tickets on the way home. Observe:
"What's this?"
"Taboo, Dad."
"Huh?"
"Yeah, Boy George wrote a show.... You know, the one Rosie's producing."
"Why would you EVER pay money to see Boy George?!"
Point being, I think people outside of the target audience were afraid of it. That said, the target audience was pretty small, unfortunately.
Its second problem was its book. The book was a WRECK. There are all of these characters that are supposed to have this joint history, and by the end of the musical they all end up together, but in many of their cases, someone watching has no clue whatsoever how or why they know each other. Because George can't act, many of his scenes were cut, and his character was pretty integral in a lot of those relationships that were just left hanging.
Those two things made for deathly reviews, and the show flopped.
A work of art is an invitation to love.