Phantom of London, over the summer I saw Avenue Q spur of the moment ( granted this is on Broadway, but I think that the point I am going to make won't matter where I saw it) and thought that I wouldn't find it as funny as I once did. However, once I got in there and sat down and the show was starting, I cracked up and had a great time. In fact, I had so much fun that I went again the next night. I think that if you take a fair amount of time between visits, you will find things funny again and find things that you didn't laugh at the first time to be things that you're now laughing at.
As for Avenue Q getting lost in a big theatre on tour, that seemed to be one of the problems before they sent it off on tour in America. But, it seemed to be not that big a deal when they did play the bigger touring houses in The States.
"If you try to shag my husband while I am still alive, I will shove the art of motorcycle maintenance up your rancid little Cu**. That's a good dear"
Tom Stoppard's Rock N Roll