I could see a few NYC comics making a more off-kilter production work. Peter Smith is non-binary and would make a beautiful Frank. Any of the Three Busy Debras would make a fun Columbia and Catherine Cohen as Magenta is a perfect match. I don't think there's any role in the show Erin Markey wouldn't kill.
Fosse, The Book of Mormon is filled with profanity but it's not a particularly sexual show. The closest we get is the baptism song which is fairly tame.
There's also Spooky Mormon Hell Dream, but to me, it seems that much of the profanity and themes of the show itself push the R envelope much further than any version of Rocky Horror I've seen (or performed). And then there's the argument that because there isn't anything really sexually explicit (though Rocky Horror is pretty tame by today's standards) on Broadway, Rocky Horror could do well for that very reason by...filling the void, shall we say...and providing some theatrical diversity on Broadway. The events of 9/11 aside, staging the revival at Circle in the Square was going to take a long time to recoup, given the size of the house.
Based on the promo video, that Stratford production looks fantastic. I saw the 1999 West End revival featuring the updates and revisions to the script and subsequently performed in the US premiere of the new script as Brad prior to the Broadway revival. Never got to see the Broadway revival, but I'd love to experience a big, loud creative production again.
Personally, I'd love to see Jake Shears as Frank. Or perhaps go in completely the opposite direction with Marc Kudisch.
"What can you expect from a bunch of seitan worshippers?" - Reginald Tresilian
Lonesome has the most incredible voice- when he sang “I’m Going Home” he didn’t do any Joan Crawford/Bette Davis schtick. He just sang, and the audience was transfixed.