When I saw The Producers, a woman in the audience laughed very loudly at EVERY SINGLE THING that Nathan Lane said. Even if it wasn't a punch line. Even if it was just a regular piece of dialogue that wasn't supposed to be funny. It was kind of ridiculous, and the audience started laughing back within the first few minutes of dialogue. Fortunately, Lane put an end to it pretty quickly by looking out over the audience with a puzzled look after her loud laughter after an ordinary line and ad-libbing something like, "Because what I said was so funny" or something like that -- it was hilarious and did not come off as mean-spirited (I can't remember exactly what he said, but it was more clever than what I just wrote), and she calmed down.
I find the people who seem to be insincerely laughing too loudly to be extremely annoying. If someone is finding the show funnier than I do, that's one thing, but if someone is forcing it, it is very distracting.
"What was the name of that cheese that I like?"
"you can't run away forever...but there's nothing wrong with getting a good head start"
"well I hope and I pray, that maybe someday, you'll walk in the room with my heart"