I'd be in heaven if Murphy reprised her turn as Anna Loewens if only so I can get to hear her sing her tour de force "Shall I Tell You What I Think of You?" live. God, she does such a perfect rendition on the cast recording.
However, she did the role already, won a Tony for it, she's moved on. Let another fantastic actress have her go at it, I for one would love to see Laura Benanti (with a great director who can get out of her a performance like the one she is giving now as Louise) or Anne Hathaway as Anna. And if they wanted to do a "non-traditional" production, Anika Noni Rose would be ideal in the role.
"Some people can thrive and bloom living life in a living room, that's perfect for some people of one hundred and five. But I at least gotta try, when I think of all the sights that I gotta see, all the places I gotta play, all the things that I gotta be at"