Depending on when you think they became "stars" - John C. Reilly and Philip Seymour Hoffman both were leading men on Broadway while they were mostly supporting players in Hollywood (and still are, to some extent.)
Also, while I second Nina Arianda as a likely bet to go big, I'll also say James Corden has a great shot at it too. He's huge as a TV star in the UK, but over here he has next-to-little fame except for his Tony win and amazing turn in GUV'NORS, so he might count (loosely).
Words don't deserve that kind of malarkey. They're innocent, neutral, precise, standing for this, describing that, meaning the other, so if you look after them you can build bridges across incomprehension and chaos. But when they get their corners knocked off, they're no good anymore…I don't think writers are sacred, but words are. They deserve respect. If you get the right ones in the right order, you can nudge the world a little.