While I agree that DEH and Great Comet seem the likeliest locks so far, but then we have War Paint, Amelie, Anastasia, Groundhog Day, and Come From Away that all have respectable reviews from pre-Broadway productions. I could frankly see any combination of those, and I can imagine this might be another 5-nominee year because there are so many quality shows coming in that nominators might be split.
Each show does have weaknesses, though, and I think it's a matter of how well the creatives can mask them and how much the critics hone in on them. War Paint is a dual-diva narrative and a star vehicle whose structure and storytelling were lukewarmly reviewed. Amelie is a very specific tone that may come across as either charming or twee. Anastasia needs rewrites, especially to its antagonist, and has to overcome the animation stigma. Groundhog Day, by its very nature, has to overcome the repetitive structure, and Come From Away, if politically and emotionally resonant, was noted to suffer from low-stakes-syndrome.
It's too early to tell how any of these will fare, although I would lean towards CFA, Anastasia, and Amelie at the moment, but that's liable to change when this barrage hits in the spring! I envy you NY'ers :)