I don't think she'll be nominated for SHREK, just because the voters are probably starting to take her for granted (this line of thinking: "Well, of course she's talented, of course she can do what she's doing, and do it so well - why do we need to acknowledge it again?")
And I back this up with Nathan Lane's lack of a nomination for NOVEMBER.
"Y'know, I think Bertolt Brecht was rolling in his grave."
-Nellie McKay on the 2006 Broadway production of The Threepenny Opera, in which she played Polly Peachum