I haven't been to many Broadway theatre personally, but from what I've been to:
PALACE: I really enjoyed the character of the Palace and how even when sitting in the second balcony, I felt pretty close to the action (I'm sure it sounds odd, but in Minneapolis our theatres are much longer and I'm used to those far seats.) The lighting was nice enough as well. I didn't enjoy the lack of leg room or how the dome above was completely unlit and just overall boring.
NEDERLANDER: I loved the rundown bohemian feel of this theatre for Rent. If I was seeing another show, I would be so appalled at the interior, but I just love it for Rent. I love the proscenium all decked out with it's broken dishes and how the whole theatre is in such disrepair. But like I said, I would only accept it for Rent. Escaping that deathtrap was kind of scary, with the entrances for the mezzanine level only at the very back of the theatre other than the one in the very center towards the top.
BROADWAY: There was no legroom. At all. But it's a BEAUTIFUL interior of a theatre. The stage is uncomfortably high (especially sitting in the 5th row), but what can you do.
MAJESTIC: I absolutely loved the Majestic. I was sitting front row and the stage was at perfect eye level. I could still see the stage floor a bit, and I loved it. The musty smell of the old place really set the mood for Phantom with me. They have a really creepy sitting area outside of the mens bathroom though. It's like it's supposed to be a sitting area but it's barely lit and has a single couch in it.
GERSHWIN: Wicked is an amazing show, but that was the only amazing thing I saw all night. I could hear fine (I was sitting in the loge), and I had great sightlines, but the place lacked any character. The seats were just a dull bluish grey and the Hall of Fame or whatever is kind of unimpressive. Overall, after all of the hype I had about the monstrous theatre, I was let down (but not by Julia and Kendra, who I find phenomenal). The only good thing was their plentitude of bathrooms. And I'd heard it was just a gigantic theatre, almost feeling like a warehouse, but I was kind of shocked. At the time (this was my very first Broadway theatre to enter), I was shocked almost to see it was much smaller than I thought. Maybe I'm just being overanalyzing though