I've seen the show twice now. The first time I saw it from the last row in the balcony and liked but didn't love it. I felt like I could tell where the jokes were trying to be funny but didn't find myself laughing organically as much as I would've expected. I was also insanely tired that day though so I figured that might've also affected my perception and I picked up a rush ticket for the evening performance tonight (orchestra right partial view, though we didn't miss much). I think being closer helped a lot in being able to see the actors and their delivery better, and I was definitely able to pick up more details in what they were doing. I was laughing a lot more and just generally had more fun (also being able to read the hats more helped a lot). I think mezz would be the ideal spot for this show, as there's some minor stuff that happens on the floor of the stage, but orchestra should be mostly fine.
I think the show itself still feels inherently like an off-Broadway show, but it's elevated by Andrew Rannells and Josh Gad as well as Alex Timbers's direction. Parts of it feel like an extended sketch comedy routine (probably not surprising considering its UCB origins), and it can get tiresome if you don't buy into the characters and what they're doing. I like how the set has a few surprises and also how they involved the band into the show, but overall the best part of it really is the performances from Andrew Rannells and Josh Gad, and they really make a fantastic comedy duo.