Act 1 remains basically the same, from what I remember. The first half of Act 2 is also the same, but the second half has been completely re-tooled (not in terms of the story, but in terms of how they tell it).
First, 'It's Getting Dark on Old Broadway' is completely gone, as are the dancers in the big headdresses with the names of old theaters on them.
What once was the song where Brooks mocks Shuffle Along as the Original Broadway Color Show (with the ensemble seated in a line, dancing with their gloved hands) now takes place in front of a scrim, while the ensemble dances and sings behind the principals, echoing 'no one will remember you'. It looks great. They quickly make the point that Shuffle Along lead to Cabin in the Sky, Ain't Misbehavin, etc. I don't think George name-checked any of his own shows in that list.
The goodbye to Florence Mills is significantly shorter, there are no reporters hounding her, she just comes out and they say how she died and she does a shorter version of her wordless song.
The 'Buddy's Blues'-esque version of 'Shuffle Along' that Brian Stokes Mitchell sang in half blackface is totally gone. He still does paint a portion of his face black, but then simply narrates what happened with Aubrey.
The final song 'Shuffle Off This Mortal Coil' is now 'Shuffle Off of Shuffle Along'. They added a minor tap number to explain what happens to the dancers and they all shout out what age they died, which I thought worked very well.