In "Everything's Coming Up Roses", Ethel Merman sings an A# instead of the written C# in the phrase "nothing's gonna stop us till we're through!". It does not mess up the harmony with the accompanying orchestra, but makes it easier for her to sing.
In the years following GYPSY when Ethel Merman toured and gave concerts with a large orchestra backing her, "Everything's Coming Up Roses" was transposed down significantly to enable her to get through her signature song successfully. Also, a noticeable vibrato crept into her singing as the years rolled by.
"Madam Rose...and her daughter...Gypsy!"