Caught this last week and was totally in love with it. As some others have said, there really isn't a bad seat, but I was in the 400s behind the band and it offered a completely unobstructed view with some really stunning stage pictures. I would recommend sitting there. However, I made the mistake of drinking two happy hour beers beforehand and desperately had to pee right before "Days and Days" and the only way out of that section requires that you walk on stage, so I ended up having to sit in the opposite section of the theater for the last 20 minutes.
I saw this while it was at the Public last year and thought it was fine, but I blame that on merely okay staging and being zombie-level exhausted. Since then, I've fallen in love with both the graphic novel and the cast recording so I was very much looking forward to a repeat visit. I'm happy to report that any issues I had with staging have been completely eradicated. Sam Gold's in-the-round staging is a masterpiece of direction and his work with the actors has only deepened (though I will regret missing Judy Kuhn's "Days and Days" forever as it's my favorite song in the score). Michael Cerveris, Judy Kuhn, and Sydney Lucas are giving exceptional performances. "Edges of the World" and "Ring of Keys" are just a joy to experience live, for totally different reasons. I'm also happy that Big Alison is more integrated into the staging, making you hyper-aware of the "memory play" framing device without diminishing her as a character. She felt totally forgettable at the Public, in my opinion. My only qualm is that "Al for Short" has been cut. The book scene that precedes where it was does a fine job of establishing Alison's dislike for girl clothes, but the song had so much fun with her burgeoning masculinity. Ah, well. It lives on in recording, at least!
Anyway, this gets my vote for Best Musical by a longshot. A totally lovely, heartbreaking, illuminating evening of theatre. Bravo and thank you to Jeanine Tesori, Lisa Kron, Sam Gold, and - most importantly - Alison Bechdel for creating such a vital piece of American theatre.